
Tetrahedron Letters p. 2371 - 2374 (1998)
Update date:2022-08-02
Topics:
Kataoka, Osamu
Kitagaki, Shinji
Watanabe, Nobuhide
Kobayashi, Jun-ichi
Nakamura, Sei-ichi
Shiro, Motoo
Hashimoto, Shun-ichi
A highly efficient construction of the 2,8-dioxabicyclo[3.2.1]octane core structure of zaragozic acids, inhibitors of the enzyme squalene synthase, has been achieved by exploiting the sequence of rhodium(II)- mediated intramolecular carbonyl ylide formati
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