Synthetic studies on selectin ligands/inhibitors: Synthesis and inhibitory activity of 2-O-fucosyl sulfatides containing 2-branched fatty alkyl residues in place of ceramide

Article abstract of DOI:10.1080/07328309808002905

To investigate the biological selectin-ligand interactions, four sulfated 2-O-α-L-fucopyranosyl β-D-galactopyranosides containing 2-branched fatty-alkyl residues in place of ceramide have been systematically synthesized. The target glycolipids were assaye

Full text of DOI:10.1080/07328309808002905

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Synthetic Studies on Selectin Ligands/
Inhibitors: Synthesis and Inhibitory
Activity of 2-O-Fucosyl Sulfatides
Containing 2-Branched Fatty Alkyl
Residues in Place of Ceramide
Takao Ikami a , Takuji Kakigami a , Kunihisa Baba a , Hitoshi
Hamajima a , Takahito Jomori a , Toshinao Usui a , Yasuo Suzuki b ,
Harunari Tanaka b , Hideharu Ishida c , Akira Hasegawa c & Makoto
Kiso c
a Drug Discovery Research Department , Sanwa Kagaku Kenkyusho
Co., Ltd. , 363 Shiosaki, Hokusei-cho, Mie, 511-04, Japan
b Department of Biochemistry , University of Shizuoka School of
Pharmaceutical Science , Shizuoka, 422, Japan
c Department of Applied Bioorganic Chemistry , Gifu University ,
Gifu, 501-11, Japan
Published online: 15 Aug 2006.
To cite this article: Takao Ikami , Takuji Kakigami , Kunihisa Baba , Hitoshi Hamajima , Takahito
Jomori , Toshinao Usui , Yasuo Suzuki , Harunari Tanaka , Hideharu Ishida , Akira Hasegawa & Makoto
Kiso (1998) Synthetic Studies on Selectin Ligands/Inhibitors: Synthesis and Inhibitory Activity of 2-
O-Fucosyl Sulfatides Containing 2-Branched Fatty Alkyl Residues in Place of Ceramide, Journal of
Carbohydrate Chemistry, 17:3, 453-470, DOI: 10.1080/07328309808002905
To link to this article: http://dx.doi.org/10.1080/07328309808002905
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