Synthesis and A1 and A(2A) adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones

DOI: 10.1016/S0014-827X(98)00006-8

Source and publish data:

Il Farmaco p. 189 - 196 (1998)

Update date:2022-07-30

Topics:

Authors:

Colotta, Vittoria

Catarzi, Daniela

Varano, Flavia

Melani, Fabrizio

Filacchioni, Guido

Cecchi, Lucia

Trincavelli, Letizia

Martini, Claudia

Lucacchini, Antonio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0014-827X(98)00006-8

A series of pyrano[2,3-c]pyrazol-4-ones was synthesized and evaluated for bovine brain adenosine A₁ and A(2A) receptor binding affinity. Substituents at positions 5 and/or 6 were varied in order to define the structure-activity relationships in

Full text of DOI:10.1016/S0014-827X(98)00006-8

Products guided by the article

Product name:1-(5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-3-(3-nitro-phenyl)-propane-1,3-dione

Cas No:210099-67-5

R&D Labs maybe for 210099-67-5

Wuhan Sunrise Pharmaceutical Technology Co., Ltd

Contact:+86-27-83314682

Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
Kono Chem Co.,Ltd

website:http://www.konochem.com

Contact:86-29-86107037

Address:No.170 West Avenue,Xi’an 710082,China
Jinan Yufeng Bioengineering Co., Ltd.

Contact:+86-531-83130545/83130528/83130525/83130505

Address:Rm415,Building2,No19,Huaneng Road,Jinan, Shandong, China
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
Jiangsu Willing Bio-Tech Co ltd

website:http://www.willingbio.com/

Contact:+86 18796908173

Address:No 18 Guoqiao Road

Relevant to this article

Reactions of primary and secondary amines with substituted hydroquinones: Nuclear amination, side-chain amination, and indolequinone formation

Doi:10.1021/jo980541v
(1998)
ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

Doi:10.1021/acschemneuro.6b00181
(2017)
Synthesis and characterization of heterobimetallic complexes with pyridyl selenolato ligands. Crystal structure of [{Pt(C₅H₄N)(SeC₅H₄N)(dppp)}ZnCl₂]

Doi:10.1016/j.jorganchem.2016.12.013
(2017)
Discovery of a potent, orally bioavailable β₃ adrenergic receptor agonist, (R)-N-[4-[2-[[2-Hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(tri fluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide

Doi:10.1021/jm000286i
(2000)
Preparation of optically active binaphthylmonophosphines (MOP's) containing various functional groups

Doi:10.1016/S0040-4020(01)89366-2
(1994)
A convenient synthetic method of a 5,7-diarylcyclopenteno-[1,2-b]pyridine-6-carboxylate: A key intermediate for potent endothelin receptor antagonists

Doi:10.1016/S0968-0896(02)00261-4
(2002)

Article Doi