Synthesis and A1 and A(2A) adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones

DOI: 10.1016/S0014-827X(98)00006-8

Source and publish data:

Il Farmaco p. 189 - 196 (1998)

Update date:2022-07-30

Topics:

Authors:

Colotta, Vittoria

Catarzi, Daniela

Varano, Flavia

Melani, Fabrizio

Filacchioni, Guido

Cecchi, Lucia

Trincavelli, Letizia

Martini, Claudia

Lucacchini, Antonio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0014-827X(98)00006-8

A series of pyrano[2,3-c]pyrazol-4-ones was synthesized and evaluated for bovine brain adenosine A₁ and A(2A) receptor binding affinity. Substituents at positions 5 and/or 6 were varied in order to define the structure-activity relationships in

Full text of DOI:10.1016/S0014-827X(98)00006-8

Products guided by the article

Product name:1-(5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-3-(3-nitro-phenyl)-propane-1,3-dione

Cas No:210099-67-5

R&D Labs maybe for 210099-67-5

Changzhou Welton Chemical Co., Ltd,

Contact:0086-519-85910828,85920537,85912897

Address:No.8 Jinlong Road, Binjiang Park, Changzhou, Jiangsu, China.
King Brother Chem Co., Ltd

website:http://www.uvchemkeys.com

Contact:0086-021-58785816

Address:RM2607 Building No.1 Guosheng, Lane 388, Zhongjiang Road, Putuo District, Shanghai 200062 China
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.

Contact:13861062998

Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Jinan Kaypharm Chemical Co.,Ltd

Contact:86-0531-86986780

Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province

Relevant to this article

Reactions of primary and secondary amines with substituted hydroquinones: Nuclear amination, side-chain amination, and indolequinone formation

Doi:10.1021/jo980541v
(1998)
ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

Doi:10.1021/acschemneuro.6b00181
(2017)
Synthesis and characterization of heterobimetallic complexes with pyridyl selenolato ligands. Crystal structure of [{Pt(C₅H₄N)(SeC₅H₄N)(dppp)}ZnCl₂]

Doi:10.1016/j.jorganchem.2016.12.013
(2017)
Discovery of a potent, orally bioavailable β₃ adrenergic receptor agonist, (R)-N-[4-[2-[[2-Hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(tri fluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide

Doi:10.1021/jm000286i
(2000)
Preparation of optically active binaphthylmonophosphines (MOP's) containing various functional groups

Doi:10.1016/S0040-4020(01)89366-2
(1994)
A convenient synthetic method of a 5,7-diarylcyclopenteno-[1,2-b]pyridine-6-carboxylate: A key intermediate for potent endothelin receptor antagonists

Doi:10.1016/S0968-0896(02)00261-4
(2002)

Article Doi