Synthesis and A1 and A(2A) adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones

DOI: 10.1016/S0014-827X(98)00006-8

Source and publish data:

Il Farmaco p. 189 - 196 (1998)

Update date:2022-07-30

Topics:

Authors:

Colotta, Vittoria

Catarzi, Daniela

Varano, Flavia

Melani, Fabrizio

Filacchioni, Guido

Cecchi, Lucia

Trincavelli, Letizia

Martini, Claudia

Lucacchini, Antonio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0014-827X(98)00006-8

A series of pyrano[2,3-c]pyrazol-4-ones was synthesized and evaluated for bovine brain adenosine A₁ and A(2A) receptor binding affinity. Substituents at positions 5 and/or 6 were varied in order to define the structure-activity relationships in

Full text of DOI:10.1016/S0014-827X(98)00006-8

Products guided by the article

Product name:1-(5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-3-(3-nitro-phenyl)-propane-1,3-dione

Cas No:210099-67-5

R&D Labs maybe for 210099-67-5

Shanghai Sinofluoro Scientific Co., Ltd

Contact:+86-21-64279360

Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
Kaymossy BioChem Tech Co., Ltd

website:http://www.kaimosi.com

Contact:0571-87191913/0571-87199097

Address:Room 215, Building 3rd, No.288 Ningxia Road, Qingdao city, China
Xi'an North Information Industry Co., Ltd. Weilv Chemical Department

Contact:+86-29-88156413

Address:Jixiang Road 99 Xi'an Shaanxi Province
Shanghai HengXun Pharmaceutical Tech. Co., Ltd.

Contact:86-86-52730756

Address:Room 603, No. 240, Tianmuzhong Road, Zhabei, Shanghai, China
Allicon Pharmaceuticals,Inc.

Contact:+86-519-86339586，13584329896

Address:Changzhou Scientific and Education Park

Relevant to this article

Reactions of primary and secondary amines with substituted hydroquinones: Nuclear amination, side-chain amination, and indolequinone formation

Doi:10.1021/jo980541v
(1998)
ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

Doi:10.1021/acschemneuro.6b00181
(2017)
Synthesis and characterization of heterobimetallic complexes with pyridyl selenolato ligands. Crystal structure of [{Pt(C₅H₄N)(SeC₅H₄N)(dppp)}ZnCl₂]

Doi:10.1016/j.jorganchem.2016.12.013
(2017)
Discovery of a potent, orally bioavailable β₃ adrenergic receptor agonist, (R)-N-[4-[2-[[2-Hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(tri fluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide

Doi:10.1021/jm000286i
(2000)
Preparation of optically active binaphthylmonophosphines (MOP's) containing various functional groups

Doi:10.1016/S0040-4020(01)89366-2
(1994)
A convenient synthetic method of a 5,7-diarylcyclopenteno-[1,2-b]pyridine-6-carboxylate: A key intermediate for potent endothelin receptor antagonists

Doi:10.1016/S0968-0896(02)00261-4
(2002)

Article Doi