Synthesis and A1 and A(2A) adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones

DOI: 10.1016/S0014-827X(98)00006-8

Source and publish data:

Il Farmaco p. 189 - 196 (1998)

Update date:2022-07-30

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Authors:

Colotta, Vittoria

Catarzi, Daniela

Varano, Flavia

Melani, Fabrizio

Filacchioni, Guido

Cecchi, Lucia

Trincavelli, Letizia

Martini, Claudia

Lucacchini, Antonio

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Article abstract of DOI:10.1016/S0014-827X(98)00006-8

A series of pyrano[2,3-c]pyrazol-4-ones was synthesized and evaluated for bovine brain adenosine A₁ and A(2A) receptor binding affinity. Substituents at positions 5 and/or 6 were varied in order to define the structure-activity relationships in

Full text of DOI:10.1016/S0014-827X(98)00006-8

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