Short synthesis of sulfatide- and SQDG-mimetics as small molecular weight selectin inhibitors

DOI: 10.1016/S0040-4020(98)00950-8

Source and publish data:

Tetrahedron p. 15189 - 15198 (1998)

Update date:2022-07-29

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Authors:

Kretzschmar, Gerhard

Toepfer, Alexander

Sonnentag, Michael

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Article abstract of DOI:10.1016/S0040-4020(98)00950-8

Small molecular weight sulfatide analogs were synthesised and tested in cell-based selectin mediated adhesion assays. The ceramide moiety of sulfatides could be replaced by simple glycerol ethers to obtain potent mimetics. The specific activity of these i

Full text of DOI:10.1016/S0040-4020(98)00950-8

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