
Tetrahedron Letters p. 4695 - 4696 (1998)
Update date:2022-07-30
Topics:
Itaya, Taisuke
Hozumi, Yoshitaka
Kanai, Tae
Ohta, Tomihisa
The title nucleoside 9 was synthesized by alkylation of 8-oxoadenosine (7) with 4-benzyloxy-3,5-dibromobenzyl bromide, followed by Dimroth rearrangement and acid hydrolysis. 2'-Deoxy version of this reaction sequence accomplished the first synthesis of aplidiamine (6).
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Doi:10.1021/om980395j
(1998)Doi:10.1002/1522-2675(200202)85:2<552::AID-HLCA552>3.0.CO;2-1
(2002)Doi:10.1021/jm00310a003
(1968)Doi:10.1021/ja981862r
(1998)Doi:10.1016/S0040-4039(98)01363-X
(1998)Doi:10.1021/jo980516p
(1998)