Transannular cyclizations of 10-membered lactams: An easy route to isoquinoline alkaloids

DOI: 10.1016/S0040-4039(98)01363-X

Source and publish data:

Tetrahedron Letters p. 6551 - 6554 (1998)

Update date:2022-07-30

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Authors:

Rodriguez, Gema

Castedo, Luis

Dominguez, Domingo

Saa, Carlos

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Article abstract of DOI:10.1016/S0040-4039(98)01363-X

Transannular cyclization of 10-membered ring lactams with hydriodic acid or fluoride gave tetrahydroprotoberberines or isoindolobenzazepines, respectively. The starting macrolactams were prepared by intramolecular addition of an aryl radical to a trimethy

Full text of DOI:10.1016/S0040-4039(98)01363-X

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