Bioorganic and Medicinal Chemistry Letters p. 2593 - 2598 (1999)
Update date:2022-09-26
Topics:
Mewshaw, Richard E.
Nelson, James A.
Shah, Uresh S.
Shi, Xiaojie
Mazandarani, Hossein
Coupet, Joseph
Marquis, Karen
Brennan, Julie A.
Andree, Terrance H.
The synthesis of several bioisosteric analogs based on the 3-OH-phenoxyethylamine dopamine D2 agonist template (i.e., 3) is described. The benzimidazol-2-ones and benzthioimidazol-2-ones (7-10) and 2-trifluoromethyl-benzimidazole (13) were obse
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