Potential antiviral agents. Part II. Synthesis and antiviral evaluation of pyrazinones substituted with acyclic chains

Article abstract of DOI:10.1080/07328319808003482

The synthesis of a series of 4'-substituted hydroxybutyl pyrazine analogues of the anti-herpes compound, acyclovir, is described. The compounds were characterized with ¹H and ¹³C nmr, mass and IR spectroscopy. Antiviral (HSV-1, CMV,

Full text of DOI:10.1080/07328319808003482

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Potential Antiviral Agents. Part II.
Synthesis and Antiviral Evaluation of
Pyrazinones Substituted With Acyclic
Chains
Jean Davis a , Rachida Benhaddou a , Olessia Fedoryak a , Robert
Granet a , Pierre Krausz a , Christophe Bliard b , Michele De Monte c
& Anne Marie Aubertin c
a Laboratoire de Chimie des Substances Naturelles , Université de
Limoges , 123, av. Albert Thomas, Limoges cedex, 87060, France
b CNRS, ESA 6013 , CRPB Europol′agro, Faculté des Sciences , Moulin
de la Housse, Reims cedex, 51097, France
c INSERM U 74 , Institut de Virologie, Université Louis Pasteur , 3 rue
Koeberlé, Strasbourg, 67000, France
Published online: 21 Aug 2006.
To cite this article: Jean Davis , Rachida Benhaddou , Olessia Fedoryak , Robert Granet , Pierre
Krausz , Christophe Bliard , Michele De Monte & Anne Marie Aubertin (1998) Potential Antiviral
Agents. Part II. Synthesis and Antiviral Evaluation of Pyrazinones Substituted With Acyclic Chains,
Nucleosides and Nucleotides, 17:8, 1489-1504, DOI: 10.1080/07328319808003482
To link to this article: http://dx.doi.org/10.1080/07328319808003482
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