A general and regiospecific synthesis of 5,8-disubstituted α- tetralones

Article abstract of DOI:10.1080/00397919808004457

A Pd[0]-mediated Stille coupling strategy was developed to prepare unsymmetrically 5,8-disubstituted α-tetralones in high yield. The compounds synthesized by this route are representative of the ease with which functionality may be introduced into the tet

Full text of DOI:10.1080/00397919808004457

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Synthetic Communications:
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A General and Regiospecific
Synthesis of 5,8-
Disubstituted α-Tetralones
M. D. Rosen a b , M. D. Doubleday a & M. J. Suto
a
a Department of Medicinal Chemistry , Signal
Pharmaceuticals, Inc. , 5555 Oberlin Drive, San
Diego, CA, 92121
b Department of Chemistry , University of
California , Irvine, CA, 92717
Published online: 22 Aug 2006.
To cite this article: M. D. Rosen , M. D. Doubleday & M. J. Suto (1998) A
General and Regiospecific Synthesis of 5,8-Disubstituted α-Tetralones, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 28:18, 3491-3502, DOI: 10.1080/00397919808004457
To link to this article: http://dx.doi.org/10.1080/00397919808004457
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