PRACTICAL PREPARATION AND METALLO-ENE REACTIONS OF (2-ALKENYLALLYL)-MAGNESIUM CHLORIDES: COMPARATIVE STUDY OF MAGNESIUM ACTIVATION

Article abstract of DOI:10.1016/S0040-4039(01)81370-8

Magnesium activated by equilibration with its anthracene adduct in THF metalates smoothly 2-alkenyl chlorides at -65 deg C without significant coupling.The resulting solutions of Grignard reagents are subjected to thermal (80-130 deg C) cyclization followed by trapping with electrophiles.