Classical/nonclassical hybrid cannabinoids: Southern aliphatic chain- functionalized c-6β methyl, ethyl, and propyl analogues

DOI: 10.1021/jm960677q

Source and publish data:

Journal of Medicinal Chemistry p. 3596 - 3608 (1998)

Update date:2022-07-29

Topics:

Authors:

Drake, David J.

Jensen, Rader S.

Busch-Petersen, Jakob

Kawakami, Joel K.

Fernandez-Garcia, M. Concepcion

Fan, Pusheng

Makriyannis, Alexandros

Tius, Marcus A.

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Article abstract of DOI:10.1021/jm960677q

The stereoelectronic requirements for interaction of the southern aliphatic hydroxyl of cannabimimetic pharmacophores with the CB1 and CB2 receptors are explored. The stereoselective syntheses of three series of classical/nonclassical hybrid cannabinoids

Full text of DOI:10.1021/jm960677q

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