Bioorganic and Medicinal Chemistry Letters p. 1719 - 1722 (2002)
Update date:2022-08-05
Topics:
Borthwick, Alan D.
Exall, Anne M.
Haley, Terry M.
Jackson, Deborah L.
Mason, Andrew M.
Weingarten, Gordon G.
Mechanism-based inhibitors of HCMV protease, which are stable to human plasma (≥20 h) and have single-figure potency in the μM range against HCMV protease, have been developed based on the dansylproline α-methyl pyrrolidine-5,5-trans-lactam nucleus.
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