Synthesis of the Vitamin E amino acid esters with an enhanced anticancer activity and in silico screening for new antineoplastic drugs

DOI: 10.1016/j.ejps.2016.04.008

Source and publish data:

European Journal of Pharmaceutical Sciences p. 59 - 69 (2016)

Update date:2022-07-30

Topics: Characterization Molecular docking Optimization Data Analysis Biological Assays Publication and Reporting Target Selection Experimental Validation Selection of Amino Acids In Silico Screening

Authors:

Gagic, Zarko

Ivkovic, Branka

Srdic-Rajic, Tatjana

Vucicevic, Jelica

Nikolic, Katarina

Agbaba, Danica

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Article abstract of DOI:10.1016/j.ejps.2016.04.008

Tocopherols and tocotrienols belong to the family of vitamin E (VE) with the well-known antioxidant properties. For certain α-tocopherol and γ-tocotrienol derivatives used as the lead compounds in this study, antitumor activities against various cancer ce

Full text of DOI:10.1016/j.ejps.2016.04.008

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