Tetrahedron p. 13371 - 13390 (1998)
Update date:2022-08-04
Topics: Total synthesis Alkaloid Cyclopeptide
East, Stephen P.
Shao, Feng
Williams, Lorenzo
Joullie, Madeleine M.
The naturally occurring cyclopeptide alkaloid sanjoinine G1 and its C- 11 epimer were synthesized in 18 steps from D-serine. The key steps in the synthesis were the formation of the alkylaryl ether linkage via an S(N)Ar reaction with 4-fluorobenzonitrile
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(1998)
