Total synthesis of the cyclopeptide alkaloid sanjoinine G1 and its C-11 epimer

DOI: 10.1016/S0040-4020(98)00808-4

Source and publish data:

Tetrahedron p. 13371 - 13390 (1998)

Update date:2022-08-04

Topics: Total synthesis Alkaloid Cyclopeptide

Authors:

East, Stephen P.

Shao, Feng

Williams, Lorenzo

Joullie, Madeleine M.

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Article abstract of DOI:10.1016/S0040-4020(98)00808-4

The naturally occurring cyclopeptide alkaloid sanjoinine G1 and its C- 11 epimer were synthesized in 18 steps from D-serine. The key steps in the synthesis were the formation of the alkylaryl ether linkage via an S(N)Ar reaction with 4-fluorobenzonitrile

Full text of DOI:10.1016/S0040-4020(98)00808-4

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