Comparative probe for stacking interactions in simple A:T base pair mimics

Article abstract of DOI:10.1016/S0040-4039(98)01498-1

The design and synthesis of a new seaffold for the assembly of receptor models, soluble in organic solvent, is described. It was converted into a simple receptor for 9 butyladenine and compared to other isosteric AT base pair mimics. The results support the Sanders and Hunter π stacking model.