Tetrahedron p. 5609 - 5616 (1997)
Update date:2022-08-03
Topics:
Easton, Christopher J.
Eichinger, Sharon K.
Pitt, Michael J.
Nickel peroxide selectively cleaves the α-carbon-nitrogen bond of glycine residues in dipeptide derivatives to give the corresponding amides. The glycine selectivity is attributable to preferential complexation of the reactant residue to nickel peroxide and subsequent reaction via a stable α-centered glycyl radical. The oxidation process serves as a chemical model for peptidylglycine α-amidating monooxygenase (PAM) and, in addition, may have potential for the synthesis of α,β-didehydro amino acid residues within peptides.
View MoreContact:+86-13236304423
Address:heping street NO.828,weifang city,shandong province,china
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Jiangxi Global Natural Spice Co., Ltd.
website:https://www.jxhqxl.com/
Contact:+86-796-8106598
Address:No.89, Wenshan Road,South Industrial Park, Jishui County,Jiangxi Province
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED
Contact:86-419-2390789
Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Xi'an Costrong Pharmaceutical Co., Ltd.
Contact:029- 68576496
Address:Room 2004,Shuibao Building,No.190,South Erhuan Rd, Yanta District,Xi'an,Shaan Xi,China
Doi:10.1021/jo981393b
(1999)Doi:10.1016/0022-328X(80)83008-7
(1988)Doi:10.1002/anie.202014796
(2021)Doi:10.1016/S0022-1139(00)83080-8
(1987)Doi:10.1016/S0040-4039(01)02399-1
(2002)Doi:10.1021/ja01641a002
(1954)