(1-Benzylindole-3-yl)alkanoic acids; novel nonsteroidal inhibitors of steroid 5α-reductase (I)

DOI: 10.1248/cpb.46.1683

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1683 - 1687 (1998)

Update date:2022-07-31

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Authors:

Sawada, Kozo

Hirai, Hideo

Golden, Patrick

Okada, Satoshi

Sawada, Yuki

Hashimoto, Masashi

Tanaka, Hirokazu

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Article abstract of DOI:10.1248/cpb.46.1683

A novel series of indole-3-alkanoic acids with varied N-benzyl substituents were synthesized as nonsteroidal inhibitors of steroid 5α- reductase. The structure-activity relationships in this series were studied and the optimum carboxylic acid side chain w

Full text of DOI:10.1248/cpb.46.1683

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Product name:4-[1-(6,6-Dimethyl-6H-dibenzo[b,d]pyran-3-ylmethyl)-1H-indol-3-yl]butyric acid

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