Tetrahedron Letters p. 1027 - 1029 (2002)
Update date:2022-07-31
Topics:
Hortala, Laurent
Moberg, Christina
Levacher, Vincent
Bourguignon, Jean
Dupas, Georges
A significant acceleration of acyl transfer has been achieved on 8-acetoxy-2-oxazolinylquinoline in the presence of benzylamine. Comparison of the aminolysis by the new acylating reagent with that of 8-acetoxyquinoline and 8-acetoxyquinoline-2-carbonitrile has been carried out. The results of these experiments suggest that the proximity of a supplementary basic atom to the ester group increases the participation effect of the basic site mainly by formation of a possible second hydrogen bond. The association constant of benzylamine into the basic cavity of 8-methoxy-2-oxazolinylquinoline (Ka=80 M-1) has been measured by 1H NMR titration experiments.
View MoreContact:0091-265-2313036
Address:311, ATLANTIS HEIGHTS SARABHAI MAIN ROAD,VADIWADI ,VADODARA
Inner Mongolia Xinhong Biotechnology Co., Ltd.
website:http://www.nmgxhbio.com/
Contact:+86-471-8158243
Address:No.8 Jinshan Avenue,Jinshan Economic&Technological Development Zone, TuMoTe Left flagVendor
Tianjin Boron PharmaTech Co.,Ltd.(expird)
Contact:86-022-59845187
Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
Hubei Sky Lake Chemical Co., Ltd.
Contact:+86-27-87385545
Address:Te-2, Xijiao Chemical Park, Yuekou Town, Tianmen, Hubei, China.
Xinxiang Junlong Biological Technology Co., Ltd.
website:https://junlongbio.lookchem.com/
Contact:86-13525059581
Address:Xinxiang City, Henan Province
Doi:10.1248/cpb.12.516
(1964)Doi:10.1039/jr9520004657
(1952)Doi:10.1055/s-0033-1358679
(2014)Doi:10.1107/S0108270196009109
(1996)Doi:10.1021/jacs.1c03228
(2021)Doi:10.1016/j.ejmech.2021.113513
(2021)