Tetrahedron Letters p. 9539 - 9542 (1998)
Update date:2022-07-30
Banfi, Luca
Guanti, Giuseppe
Rasparini, Marcello
A series of simple monocyclic β-lactams bearing side-chains, containing amino groups, have been synthesized, and the rate of their intramolecular transamidation studied. Protection of the amino group with an enzymatically cleavable group, allows us to selectively control the ring enlargement process.
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