Synthesis of polyazacyclophane-intercalator conjugates for combinatorial chemistry and RNA interaction studies

Article abstract of DOI:10.1002/jhet.5570370403

Anthraquinone and pyrene intercalators were conjugated to different positions of several polyazapyridinocyclophanes by various linkers to provide thirteen new polyazacyclophane-intercalator conjugates 1-13. These resulting conjugates contain two or three constrained secondary nitrogen atoms on the ring, which may serve as nucleophilic, coordinating or hydrogen-bonding sites for combinatorial, RNA interaction and coordination studies.