
Tetrahedron p. 2581 - 2590 (1999)
Update date:2022-08-04
Topics:
Toshima, Hiroaki
Sato, Hiroji
Ichihara, Akitami
The first total synthesis of (2S,3R,5S)-(-)-2,3-dihydroxytetradecan-5- olide (1), a new biologically active δ-lactone produced by Seiridium unicome, was accomplished from (R)-malic acid. In connection with the determination of the absolute configuration of 1, (2R,3S,5R)-(+)-2,3- dihydroxytetradecan-5-olide (ent-1) was also synthesized from D-glucose.
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Doi:10.1038/nature17185
(2016)Doi:10.1039/a809081e
(1999)Doi:10.1016/S0040-4039(98)02708-7
(1999)Doi:10.1021/jm981033g
(1999)Doi:10.1016/j.cclet.2019.05.013
(2019)Doi:10.1021/jo9824192
(1999)