A tripartite asymmetric allylboration - Silicon tethered alkene ring closing metathesis - In situ ring opening protocol for the regiospecific generation of functionalized (E)-disubstituted homoallylic alcohols

Article abstract of DOI:10.1016/S0040-4020(98)01135-1

Molybdenum carbene 6 catalyzed ring closing metathesis of (alkenyl)silyl ethers of homochiral allylic alcohols to afford 1,2-oxasilines which were elaborated in situ to give (E)-4-alkyl-1,2-disubstituted 3-buten-1-ol and (Z)-4-alkyl-4-silyl-1,2-disubstituted 3-buten-1-ol derivatives as single geometric isomers.