Synthesis of glucuronides of multidrug resistance reversing drug MS-209

DOI: 10.1016/S0960-894X(99)00056-6

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 659 - 662 (1999)

Update date:2022-07-29

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Authors:

Suzuki Suzuki

Mabuchi Mabuchi

Fukazawa

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Article abstract of DOI:10.1016/S0960-894X(99)00056-6

We synthesized the glucuronides of MS-209 to identify the two main unknown metabolites in human urine. Reaction of MS-209 and glucuronyl trichloroacetimidate gave two β-isomers, which were each glucuronate of(R)- and (S)-MS-209. These spectrum data were i

Full text of DOI:10.1016/S0960-894X(99)00056-6

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