Total syntheses of (±)-cryptopleurine, (±)-antofine and (±)- deoxypergularinine

Article abstract of DOI:10.1016/S0040-4020(99)00017-4

The alkaloids (±)-cryptopleurine 1, (±)-antofine 2, and (±)- deoxypergularinine 3 were synthesized by Pictet-Spengler cyclization of the 2-arylmethylpiperidine and -pyrrolidines 4, 5 and 6 obtained by sequential N- deprotection-reduction of the parent ene