Stereoselective synthesis of methyl trans-chrysanthemate and related derivatives

Article abstract of DOI:10.1016/S0040-4039(98)00160-9

γ-hydroxyalkenylstannanes, readily available from α,β- unsaturated esters, α,β-unsaturated aldehydes and tri(n- butyl)stannyllithium, react with boron trifluoride etherate to produce vinyl cyclopropane carboxylic esters. An original highly convergent synthesis of chrysanthemic acid is reported.