Diastereoselective reduction of acyclic hydroxyketones and diketones with an indium hydride reagent

DOI: 10.1016/S0040-4020(97)10024-2

Source and publish data:

Tetrahedron p. 15685 - 15690 (1997)

Update date:2022-08-05

Topics:

Authors:

Yamada, Masafumi

Horie, Tomoaki

Kawai, Masao

Yamamura, Hatsuo

Araki, Shuki

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Article abstract of DOI:10.1016/S0040-4020(97)10024-2

Hydroxyketones and diketones have been reduced with lithium indium hydride to give meso-diols selectively. α-Hydroxyketones and α-diketones are reduced to meso-1,2-diols with high diastereoselectivities, whereas the selectivities of β-hydroxyketones and β-diketones are less satisfactory.

Full text of DOI:10.1016/S0040-4020(97)10024-2

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