Diastereoselective reduction of acyclic hydroxyketones and diketones with an indium hydride reagent

DOI: 10.1016/S0040-4020(97)10024-2

Source and publish data:

Tetrahedron p. 15685 - 15690 (1997)

Update date:2022-08-05

Topics:

Authors:

Yamada, Masafumi

Horie, Tomoaki

Kawai, Masao

Yamamura, Hatsuo

Araki, Shuki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)10024-2

Hydroxyketones and diketones have been reduced with lithium indium hydride to give meso-diols selectively. α-Hydroxyketones and α-diketones are reduced to meso-1,2-diols with high diastereoselectivities, whereas the selectivities of β-hydroxyketones and β-diketones are less satisfactory.

Full text of DOI:10.1016/S0040-4020(97)10024-2

Products guided by the article

Product name:4,5-Octanediol, (4R,5S)-rel-

Cas No:22520-41-8

R&D Labs maybe for 22520-41-8

TIC Gums, Inc.

Contact:410-273-7300; 800-221-3953

Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao
Jinan Hongfangde Pharmatech Co.,Ltd

Contact:86-531-88870908

Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
Beijing Cooperate Pharmaceutical Co.,Ltd

website:http://www.cooperate-pharm.com/

Contact:86-01060279497

Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China

Relevant to this article

Diversity-oriented synthesis of bicyclic and tricyclic alkaloids

Doi:10.1039/b917965h
(2010)
Doi:10.1016/S0008-6215(00)81523-2
(1968)
A Concise Strategy for the Syntheses of Indole Alkaloids of the Heteroyohimboid and Corynantheioid Families. Total Syntheses of (+/-)-Tetrahydroalstonine, (+/-)-Cathenamine, and (+/-)-Geissoschizine

Doi:10.1021/ja00225a068
(1988)
Mixed chloride/amine complexes of dimolybdenum(II,II). 3. Preparation, characterization, and crystal structure of Mo₂Cl₄(NH₂R)₄ (R = Et, Prⁿ, Bu^t, Cy): First quadruply-bonded dimolybdenum compounds with primary amine ligands

Doi:10.1021/ic981289c
(1999)
Silver-Catalyzed Synthesis of Substituted Pyridine Derivatives from N-Propargylic α-Enamino Esters

Doi:10.1002/ejoc.201700559
(2017)
Synthesis and evaluation of 1,2,8,8a-tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: Impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis

Doi:10.1021/jo000297j
(2000)

Article Doi