Regioselective alkylation and arylation at the 6-position of pyrimidine: Synthesis of 5-alkyl-6-arylmethyl-2,4-pyrimidinediones

Article abstract of DOI:10.1080/00397919908086130

5-Alkyl-2,4,6-trichloropyrimidines reacted with various nucleophiles to afford the regioselectivity 6-substituted pyrimidines as the major products in good yields, which were transformed to 5-alkyl-6-arylmethyl-2,4- pyrimidinediones of a key intermediate

Full text of DOI:10.1080/00397919908086130

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Synthetic Communications: An
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Regioselective Alkylation and
Arylation At The 6-Position
Of Pyrimidine: Synthesis Of
5- Alkyl-6-Arylmethyl-2,4-
Pyrimidinediones
Yeon Soo Lee a & Yong Hae Kim b
a Korea Research Institute of Chemical Technology,
Taejon, 305-343, Korea
b Department of Chemistry, Korea Advanced
Institute of Science and Technology, Taejon,
305-606, Korea
Published online: 17 Sep 2007.
To cite this article: Yeon Soo Lee & Yong Hae Kim (1999): Regioselective Alkylation
and Arylation At The 6-Position Of Pyrimidine: Synthesis Of 5- Alkyl-6-Arylmethyl-2,4-
Pyrimidinediones, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 29:9, 1503-1517
To link to this article: http://dx.doi.org/10.1080/00397919908086130
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