Tetrahedron Letters p. 4137 - 4140 (1997)
Update date:2022-08-05
Topics: Experimental Route
Bermudez
Del Campo
Sinisterra
Llama
Amino-2-propanol structures can be obtained by addition to dibenzyl acetals of in situ generated dihalocarbenes using LTV (Low Valent Titanium). This methodology can be used to obtain adrenergic β-blockers with amino-2-propanol structure. Tetrahalomethane are the best dihalocarbene precursors. The yields obtained using halofluromethanes can be increased by addition of carbontetrachloride. A process that can imply halogen transfer may be proposed.
View MoreContact:+86-021-6989-5597
Address:No.80 Yichuan Rd., Putuo District,Shanghai,P.R.China
Wuxi D-Stone International Co., Ltd.
Contact:+86-510-82740567
Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China
Xinchang Jiu Xin Pharmaceutical Co., Ltd
website:http://www.jiuxinpharm.com
Contact:86 137 5756 8585
Address:Poyang industry Park
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
ALPHA PHARMACEUTICAL CO，LTD JIANGSU
Contact:+86-527-84829968,+86-527-84829998
Address:suqian city
Doi:10.1016/0022-328X(89)88037-4
(1989)Doi:10.1021/jo00829a040
(1970)Doi:10.1002/cctc.201901384
(2020)Doi:10.1016/S0960-894X(99)00086-4
(1999)Doi:10.1002/adsc.202000290
(2020)Doi:10.1016/S0040-4020(99)00861-3
(1999)
