Synthesis studies of structural analogues of tagetitoxin: 4-O-acetyl-3- amino-1,6-anhydro-3-deoxy-D-gulose 2-phosphate

Article abstract of DOI:10.1016/S0040-4020(99)00327-0

Synthetic approaches to structural analogues of tagetitoxin (1) are described. The successful route to analogue 3 (X=O) has, as a key step, protection of the cis-vicinal amino alcohol moiety of compound 7 as an N- benzylated cyclic carbamate (9). X-Ray cr