Journal of Medicinal Chemistry p. 2967 - 2980 (2007)
Update date:2022-08-03
Topics:
Ye, Bin
Arnaiz, Damian O.
Chou, Yuo-Ling
Griedel, Brian D.
Karanjawala, Rushad
Lee, Wheeseong
Morrissey, Michael M.
Sacchi, Kama L.
Sakata, Steven T.
Shaw, Kenneth J.
Wu, Shung C.
Zhao, Zuchun
Adler, Marc
Cheeseman, Sarah
Dole, William P.
Ewing, Janice
Fitch, Richard
Lentz, Dao
Liang, Amy
Light, David
Morser, John
Post, Joseph
Rumennik, Galina
Subramanyam, Babu
Sullivan, Mark E.
Vergona, Ron
Walters, Janette
Wang, Yi-Xin
White, Kathy A.
Whitlow, Marc
Kochanny, Monica J.
There remains a high unmet medical need for a safe oral therapy for thrombotic disorders. The serine protease factor Xa (fXa), with its central role in the coagulation cascade, is among the more promising targets for anticoagulant therapy and has been the
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