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Quinolines as potent 5-lipoxygenase inhibitors: Synthesis and biological profile of L-746,530

DOI: 10.1016/S0960-894X(98)00201-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1255 - 1260 (1998)

Update date:2022-08-03

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Authors:

Dube, DanielDube, Daniel

Blouin, MarcBlouin, Marc

Brideau, ChristineBrideau, Christine

Chan, Chi-ChungChan, Chi-Chung

Desmarais, SylvieDesmarais, Sylvie

Ethier, DianeEthier, Diane

Falgueyret, Jean-PierreFalgueyret, Jean-Pierre

Friesen, Richard W.Friesen, Richard W.

Girard, MarioGirard, Mario

Girard, YvesGirard, Yves

Guay, JocelyneGuay, Jocelyne

Riendeau, DenisRiendeau, Denis

Tagari, PhilipTagari, Philip

Young, Robert N.Young, Robert N.

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Article abstract of DOI:10.1016/S0960-894X(98)00201-7

Leukotriene biosynthesis inhibitors have potential as new therapeutic agents for asthma and inflammatory diseases. A series of novel substituted 2- cyanoquinolines have been synthesized and the structure activity relationships were evaluated with respect

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Full text of DOI:10.1016/S0960-894X(98)00201-7

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Product name:3-furan-3-yl-N-(3-methoxy-phenyl)-3-oxo-propionamide

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