Convergent strategies for the attachment of fluorescing reporter groups to peptide nucleic acids in solution and on solid phase

Article abstract of DOI:10.1002/1521-3765(20010917)7:18<3911::AID-CHEM3911>3.0.CO;2-1

The site-selective conjugation of peptide nucleic acids (PNA) with fluorescent reporter groups is essential for the construction of hybridisation probes that can report the presence of a particular DNA sequence. This paper describes convergent methods for