Domino imine condensation/intramolecular polar [4π+ + 2π]-cycloaddition of anilines and ω-unsaturated aldehydes: A versatile tool for the highly diastereoselective synthesis of 1,2,3,4,4a,9,9a,10-octahydroacridines

DOI: 10.1002/prac.19963380189

Source and publish data:

Journal fur Praktische Chemie - Chemiker-Zeitung p. 468 - 478 (1996)

Update date:2022-08-04

Topics:

Authors:

Beifuss, Uwe

Gehm, Henning

Herde, Andreas

Ledderhose, Sabine

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Article abstract of DOI:10.1002/prac.19963380189

The highly diastereoselective synthesis of substituted 1,2,3,4,4a,9,9a,10-octahydroacridines 7, 8 with five stereogenic centers has been achieved by domino imine condensation/intramolecular polar [4π⁺ + 2π]-cycloaddition of anilines 3 and ω-uns

Full text of DOI:10.1002/prac.19963380189

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