Stereoselective access to substituted enediyne building blocks

Article abstract of DOI:10.1016/S0040-4039(99)00813-8

Intermolecular coupling-elimination of disubstituted propargyl bromides gives rise to differentially substituted 3-hexen-1,5-diynes with E:Z selectivity as high as 100:1. Application of the methodology in the synthesis of key nanomaterial building blocks