Studies on the synthesis of tedanolide: synthesis of the C(5)-C(21) segment via a highly stereoselective fragment assembly aldol reaction of a chiral beta,gamma-unsaturated methyl ketone.

DOI: 10.1021/ol990572s

Source and publish data:

Organic letters p. 95 - 98 (1999)

Update date:2022-08-05

Topics:

Authors:

Roush Roush

Lane Lane

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Article abstract of DOI:10.1021/ol990572s

[formula: see text] A highly diastereoselective synthesis of 3, corresponding to the C(5)-C(21) segment of tedanolide, has been accomplished by a route utilizing the aldol reaction of aldehyde 4 and the beta,gamma-unsaturated methyl ketone 5.

Full text of DOI:10.1021/ol990572s

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