Synthesis of Modified Partial Structures of the Bacterial Cell Wall. 1. Lipopeptides Containing Nonproteinogenic Amino Acids

Article abstract of DOI:10.1021/jo00055a022

Two stereoisomeric lipopeptides 1 and 2 which can be regarded as modified peptidoglycans have been synthesized by using three different reaction sequences.The ene reaction of the α-allylated dipeptide 12 with butyl glyoxylate was used as a key step.The re