Bioorganic and Medicinal Chemistry Letters p. 2309 - 2314 (1999)
Update date:2022-07-29
Topics:
Cheraiti
Brik
Bricard
Keita
Nadjo
Gaudemer
A new tetra-catecholamide compound N5,N6-thiodipropanoyl-bis[N1,N10- bis(2,3-dihydroxybenzoyl-spermidine)] (H8L) has been synthesised as an iron chelator of Fe (III). Cyclic voltammogram of the iron complex H2LFe run under an argon atmosphere shows a quasi-reversible redox process with E0 = - 430 mV vs. SCE in CH3OH/H2O (60/40). This value approaches the range of biological reductants and consequently the complex may mimic the release of iron from enterobactin to the agents which are directly involved in cell metabolism.
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Doi:10.1080/00397910600978564
(2007)Doi:10.1016/S0022-328X(99)00314-9
(1999)Doi:10.1016/S0040-4039(99)01339-8
(1999)Doi:10.1016/S0022-328X(00)86794-7
(1982)Doi:10.1021/om9903442
(1999)Doi:10.1271/bbb.64.2723
(2000)
