
Tetrahedron Letters p. 5009 - 5012 (1999)
Update date:2022-08-04
Topics:
Breuil-Desvergnes, Valerie
Compain, Philippe
Vatele, Jean-Michel
Gore, Jacques
α-Lithio methoxy allene reacts with SAMP-hydrazones to give α-allenyl hydrazines 5 or 3-methoxy-3-pyrrolines 6 depending on the nature of the solvent. Both compounds have been obtained with d.e. ≥ 99 %. Hydrogenolysis of the N-N bond of 6 affords the pyrroline 7 in enantiopure form.
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(1999)