
Tetrahedron Letters p. 3767 - 3770 (1990)
Update date:2022-08-03
Topics:
Ramon, Diego J.
Yus, Miguel
The reaction of 2-(3-lithiopropyl)-1,3-dioxolane (2), prepared in situ by lithiation of the chloroacetal 1 with lithium naphthalenide at -78 deg C, with aldehydes and ketones followed by hydrolysis with hydrochloric acid and final oxidation with PCC or Jones reagent yields the corresponding δ-lactones 5.
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Doi:10.1002/jps.2600580727
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