Studies towards the synthesis of lophotoxin and pukalide: Synthesis of the 14-membered macrocyclic core and some acyclic structural analogues.

DOI: 10.1016/S0040-4039(99)01119-3

Source and publish data:

Tetrahedron Letters p. 5807 - 5810 (1999)

Update date:2022-08-03

Topics:

Authors:

Paterson, Ian

Brown, Rebecca E.

Urch, Christopher J.

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Article abstract of DOI:10.1016/S0040-4039(99)01119-3

The 14-membered macrocycle 3, an advanced intermediate in a synthetic approach to lophotoxin, was prepared from stannane 20 using an intramolecular Stille coupling. The acyclic structural analogues 6 and 7 were obtained by analogous intermolecular coupling reactions.

Full text of DOI:10.1016/S0040-4039(99)01119-3

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