Synthesis of the C-ring fragment of cobyric acid

DOI: 10.1016/S0040-4039(99)01134-X

Source and publish data:

Tetrahedron Letters p. 6197 - 6199 (1999)

Update date:2022-08-04

Topics:

Authors:

Mulzer, Johann

Riether, Doris

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Article abstract of DOI:10.1016/S0040-4039(99)01134-X

An efficient stereocontrolled synthesis of the C-ring fragment of cobyric acid 1 is described. The key step is an auxiliary controlled conjugate addition of vinyl cuprate to (5S)-menthyloxy-2[5H]-furanone 3.

Full text of DOI:10.1016/S0040-4039(99)01134-X

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