Synthesis of α-Hydroxycarboxamides from Acetonides of α-Hydroxycarboxylic Acids and Primary Amines

Article abstract of DOI:10.1055/s-1985-31460

The reaction of acetonides of α-hydroxycarboxylic acids with primary amines on heating provides a useful synthetic route to N-substituted α-hydroxycarboxamides.In general, formation of the α-hydroxycarboxamides is favored by the presence of only small sub