Chemistry Letters p. 879 - 880 (1999)
Update date:2022-07-30
Topics:
Yamago, Shigeru
Yanagawa, Masao
Nakamura, Eiichi
Thermal hetero [3 + 2] cycloaddition reaction of a dipolar trimethylenemethane 2 with an N-acyl or N-tosyl imine gives an α-methylene-γ-pyrrolidone acetal 4 in high yield, which upon hydrolysis affords a γ-amino acid derivative.
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