Irreversible enzyme inhibitors. CLV. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 1-[4-(omega-aminoalkoxy)-3-chlorophenyl]-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazines bearing a terminal sulfonyl fluoride.

DOI: 10.1021/jm00304a025

Source and publish data:

Journal of medicinal chemistry p. 672 - 676 (1969)

Update date:2022-07-29

Topics:

Authors:

Baker Baker

Janson Janson

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