
Bioscience, Biotechnology and Biochemistry p. 2025 - 2027 (1999)
Update date:2022-08-04
Topics:
Ganaha, Makoto
Yamauchi, Satoshi
Kinoshita, Yoshiro
The synthesis of methyl (S)-(-)-6,8-dihydroxyoctanoate as a precursor of (R)-(+)-α-lipoic acid was accomplished by using methyl (S)-(-)-(2-oxocyclohexyl)acetate, which had been obtained from baker's yeast reduction, as a chiral starting material.
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