Outer-ring stereochemical modulation of cytotoxicity in cephalostatins.

DOI: 10.1021/ol991153y

Source and publish data:

Organic letters p. 33 - 36 (2000)

Update date:2022-08-04

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Authors:

LaCour LaCour

Guo Guo

Boyd Boyd

Fuchs Fuchs

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Article abstract of DOI:10.1021/ol991153y

[structure: see text] 20- and 25'-epimers of cephalostatin 7, prepared by directed unsymmetrical pyrazine synthesis, address outer-ring topographical and stability questions and intimate an oxacarbenium ion rationale for the role in bioactivity of the spi

Full text of DOI:10.1021/ol991153y

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