Microbial Generation of (2R,3S)- and (2S,3S)-Ethyl 2-Benzamidomethyl-3-hydroxybutyrate, a Key Intermediate in the Synthesis of (3S,1'R)-3-(1'-Hydroxyethyl)azetidin-2-one

DOI: 10.1039/P19930002247

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Journal of the Chemical Society. Perkin transactions I p. 2247 - 2250 (1993)

Update date:2022-08-02

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Authors:

Fuganti, Claudio

Lanati, Simonetta

Servi, Stefano

Tagliani, Auro

Bedeschi, Angelo

Franceschi, Giovanni

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Article abstract of DOI:10.1039/P19930002247

Microbial reduction of the carbonyl group of the substituted acetoacetate esters 3-6 affords directly, or after Ni-Raney desulfurization, the corresponding enantiomerically pure 3S carbinols of variable diastereoisomeric composition.These compounds are tr

Full text of DOI:10.1039/P19930002247

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