Synthesis of novel C7-aryl substituted pyrrolo[2,i- c][1,4]benzodiazepines (PBDs) via pro-N10-Troc protection and Suzuki coupling

DOI: 10.1016/S0960-894X(97)10083-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3017 - 3018 (1998)

Update date:2022-08-05

Topics:

Authors:

Guiotto, Andrea

Howard, Philip W.

Giovanni Baraldi, Pier

Thurston, David E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)10083-X

Novel C7-aryl pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) have been synthesized via Suzuki coupling between a 7-Iodo N10-Troc-protected PBD carbinolamine and commercially available boronic acids.

Full text of DOI:10.1016/S0960-894X(97)10083-X

Products guided by the article

Product name:(11S,11aS)-7-(3'-nitro)phenyl-10-N-(2'',2'',2''-trichloroethoxycarbonyl)-1,2,3,10,11,11a-hexahydo-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5-one

Cas No:260419-32-7

R&D Labs maybe for 260419-32-7

ANHUI WEICHI CHEMICAL CO.,LTD

website:http://www.weichichem.com

Contact:+8613912949432

Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
Evershine Chemical CO Ltd

Contact:+86-571-87010026

Address:202, Zhenhua Road,
Jinan Great Chemical Co.,Ltd.

Contact:+86-531-58668191 58668193 58668196 58661173

Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
Weifang Jahwa Chemical Co.,Ltd

Contact:0086-536-8897731,8897730

Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China

Relevant to this article

Doi:10.1039/j39700000314
(1970)
Synthesis and evaluation of novel peripherally restricted κ-opioid receptor agonists

Doi:10.1016/j.bmcl.2004.12.018
(2005)
New method for the preparation of some 2'- and 3'-trifluoromethyl-2',3'- dideoxyuridine derivatives

Doi:10.1016/S0040-4020(99)01007-8
(2000)
Synthesis and pharmacological evaluation of novel arylpiperazine derivatives as nonsteroidal androgen receptor antagonists

Doi:10.1248/cpb.52.1330
(2004)
Electrochemistry of 1,3-diazadihydroazulanone: Electrochemical reduction and oxidation of 1-tosyl-3-aryl-1,3-diazadihydroazulanone leading to migration and elimination of the tosyl group

Doi:10.3987/COM-99-8749
(2000)
Doi:10.1002/hlca.19300130407
(1930)

Article Doi