Tetrahedron Letters p. 525 - 529 (2000)
Update date:2022-09-26
Topics:
Gonda, Jozef
Zavacká, Eva
Bude?ínsky, Miloslav
Císarová, Ivana
Podlaha, Jaroslav
A new and stereoselective route to the aminoglycoside components of the antibiotics lincomycin and clindamycin is presented. The key step involves diastereoselective introduction of the amino group at C-6 of D-galactose by (3,3)-sigmatropic rearrangements of the corresponding allylic (Z)- trifluoroacetimidate and (Z)- and (E)-allylic thiocyanates. Epoxidation of the resulting trifluoroacetamide with m-CPBA led to the epoxide with high threo-selectivity.
View MoreAngelisun(Chongqing) Pharmaceutical Co., LTD.
Contact:+86-23-68030926-816
Address:D1-7 Tech & Entrepreneurs Park, Kecheng Road, Erlang Hi-Tech Areas, Chongqing, China
Henan Tianfu Chemical Co., Ltd.
website:http://www.tianfuchem.com
Contact:86-371-55170693/55170694
Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China
Shandong Shouguang Songchuan Industrial Additives Co.,Ltd
Contact:+86-536-8566856
Address:Shouguang,Shandong,China
Shanghai Hohance Chemical Co., ltd
Contact:13914753421
Address:Fl.5;Bld. 70, Lane 1500; Xinfei Road
Zhejiang Genebest Pharmaceutical Co.,Ltd.
Contact:0086-571-63532866
Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Doi:10.1055/s-1999-3164
(1999)Doi:10.1021/acs.joc.8b00946
(2018)Doi:10.1021/om990729k
(2000)Doi:10.1246/BCSJ.20200110
(2020)Doi:10.1021/ic990905h
(2000)Doi:10.1038/sj.bjp.0704173
()