Reinvestigation of the mercuration-demercuration reaction on alkylated glycals: An improved method for the preparation of 2,3-dideoxy-α,β- unsaturated carbohydrate enals

Article abstract of DOI:10.1016/j.carres.2004.05.027

Alkyl protected glycals can be easily converted into their corresponding α,β-unsaturated enals (Perlin aldehydes) in good to very good yields by reaction with HgSO₄ and aqueous 0.02N H₂SO₄ in THF or 1,4-dioxane. While the